30-Sep-2022

TrueAllele supports NGS technology with SNP, Indel and STR markers

Next-generation Sequencing (NGS) is an advanced DNA sequencing technology for forensic science identification. Cybergenetics TrueAllele® software can input and process NGS data. This pathway brings Verogen MiSeq FGx autosomal STR data into the TrueAllele Casework process.

Once NGS data is imported, downstream processing integrates seamlessly into the lab's existing TrueAllele workflow. TrueAllele can use NGS data for DNA mixture interpretation and matching, just like any other STR data source.

The Single Nucleotide Polymorphism (SNP) is a ubiquitous source of genetic variation. SNPs have been widely used in medicine for diagnosis and treatment. They were introduced into forensics for human identification and ancestry. Newer forensic NGS kits combine SNP and STR markers. Cybergenetics can use SNPs to analyze DNA mixtures. SNP data can enhance mixture separation, identifying DNA contributors through their SNP genotypes. Cybergenetics continually adds NGS, SNP and Indel markers to the TrueAllele Casework engine.

Please contact Cybergenetics for more details about NGS technology or SNP markers for your TrueAllele forensic process.